Lung cancer is not a single disease but rather a group of cancers that develop in the lung. Cancer occurs when cells mutate (change abnormally) and begin growing out of control. These cells form tumours that can often be seen on a chest X-ray.
Some tumours that form in the lung are benign (noncancerous), meaning they do not grow into surrounding areas or spread in the body. Malignant (cancerous) tumours grow into nearby tissues or spread to other parts of the body (metastasize). A biopsy is required to determine the diagnosis of a tumour that appears suspicious on imaging.
Many patients wonder why they developed lung cancer or if they are at a high risk for the disease. In general, cancer develops after the genetic material in cells changes abnormally and the cells begin growing out of control. When there are enough of these abnormal cells, they can form a tumour.
Lung cancer often is a result of chronic exposure to tobacco smoke, either from smoking or from being around second-hand smoke. It also is linked to exposure to certain substances like radon gas or asbestos, or from prior radiation treatment to or over the lungs. People who have had lung cancer before are at higher risk of recurrence. People who have a close relative who has had lung cancer are slightly higher risk of developing the disease.
Lung cancer has 2 main types. Each type is categorized by how the cancer cells look under a microscope:
Determination of stage of lung cancer at diagnosis is important to plan best treatment modality. Stage of the Cancer is described based on:
This information is also helpful in determining prognosis (probable outcome based on the experience of others).
Many early stage lung cancers can be detected by screening or incidentally as part of xrays done for other reasons. Lung cancers are often found after they produce discomfort. Signs and symptoms of lung cancer include:.
Lung cancer risk factors include:
If the diagnosis of Lung Cancer has already been made outside, we will have your results sent to our pathologists (doctors specializing in cancer diagnosis). They will review your test results and confirm or correct your diagnosis.
At our centre, the diagnostic phase is tailored to each individual patient. If further testing is required our team will work with you to determine which tests you need. Tests may include:
Blood Tests (Blood Draws)
Several blood tests are required to help establish the diagnosis and plan the further course of treatment. Our team will carefully look at all the test that might have been done and recommend additional tests if required.
To obtain the most precise understanding of your cancer, your doctor may schedule you for different types of imaging that diagnose cancer. If you have been screened elsewhere and received abnormal results, we may perform additional imaging, if needed.
If your imaging or other screening tests show that you may have cancer, you will need a biopsy. This test takes a tiny sample of cells from abnormal areas of tissue. This is done under guidenace of an imaging modality depending on the location of the tumour.
The clinical stage or the initial staging before initiation f treatment is vitally important for patients with Lung Cancer as it is not only the basis for deciding on a patient's treatment plan, but is also the basis for comparison when checking into the patient's response to treatment. This will require
Small Cell Lung Cancer
In general, small cell lung cancer patients present at a stage where the cancer has already spread beyond the lungs. Such patients are usually treated with chemotherapy. Surgery is limited to very early stage disease in patients who have not yet have lymph nodal or distant spread. It has usually spread at the time of diagnosis. So, chemotherapy is usually the main treatment. You may also have radiotherapy to treat this type of lung cancer.
Non- Small Cell Lung Cancer (NSCLC)
This cancer is treated by Surgery, Chemotherapy and Radiotherapy or in combination. If detected early Surgery appears to offer the best long-term results.